Bob DeBoo was born in Fort Worth, Texas and has been involved in music since age 10. His musical life began as a drummer in school and grunge bands, but in his early teens he gravitated to electric bass - particularly after hearing Jaco Pastorius, Stanley Clarke, Marcus Miller, and Les Claypool. His journey towards playing Jazz really took hold when he heard Ornette Coleman's "The Shape of Jazz to Come" in High School. He found a mentor in his first upright bass teacher, Michael Blanco. It wasn't long before he was playing gigs all over the DFW area.

     Bob's formal music study began at the University of North Texas (1999-2001), where he studied with Lynn Seaton and Craig Butterfield. During this time he was playing with many great Jazz musicians in the Dallas area, such as Marchel Ivery, Shelley Carroll, Quamon Fowler, and Arlington Jones, to name a few. In 2001 he was awarded a substantial scholarship to study music at the New School in Manhattan (2002-2004). At the New School Bob was surrounded and influenced by many amazing young musicians. His primary bass teachers during his New School days were Ben Street, Michael Moore, Dennis Irwin, Cameron Browne, and Johannes Weidenmuller.

     After graduating from the New School, Bob continued playing in the New York area with great musicians such as Frank Locrasto, Jeremy Pelt, Logan Richardson, Tommy Crane, and Manuel Valera. He also became more active in playing creative bands like Josh Mease's Superioirty Complex, an experimental drum-n-bass group named Doctor Oscillator, and a hip-hop group named The Piranhas. - all of which have several albums released in the early/mid-2000s. 

     An engagement to the love of his life, Beth, brought him to Saint Louis in 2006, where he has resided ever since. Bob has been incredibly active in the Jazz scene, playing with every major artist in the area. In Saint Louis he has worked often with Willie Akins, Freddie Washington, Denise Thymes, Ptah Williams, Erin Bode, Dave Stone, Adam Maness, Peter Schlamb, and Montez Coleman. A regular fixture at Jazz at the Bistro, he has been involved with many great musicians as they travel through the area - Terrell Stafford, Bruce Barth, Keyon Harrold, Adam Larson, Allison Miller, Peter Martin, Matt Wilson, Emmanuel Harrold, Houston Person, Johnny O'Neal, Chad Lefkowitz-Brown, Geoff Keezer, among many more. Bob is also active in leading his own groups - including performances at LouFest, Chesterfield Jazz Festival, and at Jazz at the Bistro. He is also known for hosting a long-running Jazz jam session at the Kranzberg Arts Center in Grand Center.

     Very involved in Jazz education as well Bob has taught for years with Jazz St. Louis' "JazzU" program, with Jazz at Lincoln Center's Jazz for Young People program, Peter Martin's Open Studio Network, and is an adjunct bass professor at Missouri State University and Jefferson College. He has also taught private lessons to many young bassists over the years and keeps a full roster of students.